Porfimer

Chemical formula: C₉₉H₁₁₀N₁₂O₁₃  Molecular mass: 1,201.537 g/mol 

Therapeutic indications

Porfimer is indicated for:

Photodynamic therapy (PDT) of high-grade dysplasia in Barrett's oesophagus

Population group: only adults (18 years old or older)

Photodynamic therapy (PDT) with porfimer is indicated for ablation of high-grade dysplasia (HGD) in patients with Barrett’s Oesophagus (BO).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Porfimer is contraindicated in the following cases:

Porphyria

Porphyria

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe hepatic impairment

Hepatic failure stage IV

Oesophageal or gastric varices, oesophageal ulcers

at least one of
Esophageal varices
Gastric varices
Ulcer of esophagus

Tracheo-oesophageal fistula, broncho-oesophageal fistula

at least one of
Tracheoesophageal fistula
Broncho-oesophageal fistula

Artery erosion

Erosion of artery

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