Prasugrel

Chemical formula: C₂₀H₂₀FNO₃S  Molecular mass: 373.441 g/mol  PubChem compound: 6918456

Active ingredient description

Prasugrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets. Since platelets participate in the initiation and/or evolution of thrombotic complications of atherosclerotic disease, inhibition of platelet function can result in the reduction of the rate of cardiovascular events such as death, myocardial infarction, or stroke.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B01AC22 Prasugrel B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AC Platelet aggregation inhibitors excl. heparin
Discover more medicines within B01AC22

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EFFIENT Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
EFIENT Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 150322-43-3
DrugBank Drug: DB06209
KEGG Drug: D05597
PubChem Compound: 6918456
RxNorm Ingredient: 613391
SNOMED-CT Concept: 443129001
Prasugrel (substance)
UNII Identifier: 34K66TBT99
PRASUGREL

Medicines

Prasugrel is an active ingredient of these brands:

United States (US)

  • EFFIENT as PRASUGREL HYDROCHLORIDE

Austria (AT)

Brazil (BR)

  • EFFIENT as PRASUGREL HYDROCHLORIDE

Croatia (HR)

Cyprus (CY)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Ecuador (EC)

  • ROZOLEX as PRASUGREL HYDROCHLORIDE

Estonia (EE)

Finland (FI)

  • EFIENT as PRASUGREL HYDROCHLORIDE

France (FR)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Germany (DE)

Ireland (IE)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Italy (IT)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Japan (JP)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Lithuania (LT)

Netherlands (NL)

  • EFIENT as PRASUGREL HYDROCHLORIDE

New Zealand (NZ)

  • EFFIENT as PRASUGREL HYDROCHLORIDE

Poland (PL)

Romania (RO)

Singapore (SG)

  • EFFIENT as PRASUGREL HYDROCHLORIDE

South Africa (ZA)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Spain (ES)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Tunisia (TN)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Turkey (TR)

  • EFFIENT as PRASUGREL HYDROCHLORIDE

United Kingdom (UK)

  • EFIENT as PRASUGREL HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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