Chemical formula: C₂₁H₂₈O₅ Molecular mass: 360.444 g/mol PubChem compound: 5755
Prednisolone is a glucocorticoid which has anti-inflammatory activity. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs are primarily used for their potent anti-inflammatory effects in disorders of many organ systems.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A01AC04 | A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AC Corticosteroids for local oral treatment | |
| A07EA01 | Prednisolone | A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EA Corticosteroids acting locally |
| C05AA04 | Prednisolone | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AA Corticosteroids |
| D07AA03 | Prednisolone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AA Corticosteroids, weak (group I) |
| D07XA02 | Prednisolone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07X Corticosteroids, other combinations → D07XA Corticosteroids, weak, other combinations |
| H02AB06 | Prednisolone | H Systemic hormonal preparations, excl. Sex hormones and insulins → H02 Corticosteroids for systemic use → H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN → H02AB Glucocorticoids |
| R01AD02 | Prednisolone | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AD Corticosteroids |
| S01BA04 | Prednisolone | S Sensory organs → S01 Ophthalmologicals → S01B Antiinflammatory agents → S01BA Corticosteroids, plain |
| S01CB02 | Prednisolone | S Sensory organs → S01 Ophthalmologicals → S01C Antiinflammatory agents and antiinfectives in combination → S01CB Corticosteroids/antiinfectives/mydriatics in combination |
| S02BA03 | Prednisolone | S Sensory organs → S02 Otologicals → S02B Corticosteroids → S02BA Corticosteroids |
| S03BA02 | Prednisolone | S Sensory organs → S03 Ophthalmological and otological preparations → S03B Corticosteroids → S03BA Corticosteroids |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PRED FORTE Eye drops, suspension | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| PREDNISOLONE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PEDIAPRED Oral solution | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| MINIMS PREDNISOLONE Single-use eye drops | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PREDNISOLONE Suppositories | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PRED MILD Eye-drops, suspension | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| PREDNISOLONE Suspension for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Prednisolone is an active ingredient of these brands:
United States (US)
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Japan (JP)Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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