Chemical formula: C₁₃H₂₀N₂O Molecular mass: 220.311 g/mol PubChem compound: 4906
Prilocaine is a toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. Action potential propagation and never function is, therefore, prevented. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
N01BB04 | Prilocaine | N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BB Amides |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
CITANEST PLAIN Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
PRILOTEKAL Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Prilocaine is an active ingredient of these brands:
United States (US)
Austria (AT)Brazil (BR)
Croatia (HR)
Estonia (EE)Finland (FI)
France (FR)Hong Kong (HK)Ireland (IE)
Israel (IL)
Italy (IT)
Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)Singapore (SG)
Spain (ES)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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