Progesterone Other names: P4

Chemical formula: C₂₁H₃₀O₂  Molecular mass: 314.462 g/mol  PubChem compound: 5994

Active ingredient description

Progesterone is a natural progestogen, the main hormone of the corpus luteum and the placenta. It acts on the endometrium by converting the proliferating phase to the secretory phase.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G03DA04 Progesterone G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03D Progestogens → G03DA Pregnen (4) derivatives
Discover more medicines within G03DA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CRINONE Vaginal gel Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PROMETRIUM Capsule FDA, National Drug Code (US) MPI, US: SPL/Old
LUTIGEST Vaginal tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CYCLOGEST Off-white pessaries Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
UTROGESTAN Capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ENDOMETRIN Vaginal insert FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 57-83-0
DrugBank Drug: DB00396
KEGG Drug: D00066
PubChem Compound: 5994
RxNorm Ingredient: 8727
SNOMED-CT Concept: 16683002
Progesterone (substance)
UNII Identifier: 4G7DS2Q64Y
PROGESTERONE

Medicines

Progesterone is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Croatia (HR)

Cyprus (CY)

Estonia (EE)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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