Progesterone Other names: P4

Chemical formula: C₂₁H₃₀O₂  Molecular mass: 314.462 g/mol  PubChem compound: 5994

Active ingredient description

Progesterone is a natural progestogen, the main hormone of the corpus luteum and the placenta. It acts on the endometrium by converting the proliferating phase to the secretory phase.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
G03DA04 Progesterone G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03D Progestogens → G03DA Pregnen (4) derivatives
Discover more medicines within G03DA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 LUTIGEST Vaginal tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 UTROGESTAN Capsule MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 PROMETRIUM Capsule MPI, US: SPL/Old FDA, National Drug Code (US)
 ENDOMETRIN Vaginal insert MPI, US: SPL/PLR FDA, National Drug Code (US)
 CYCLOGEST Off-white pessaries MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 CRINONE Vaginal gel MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 57-83-0
DrugBank Drug: DB00396
KEGG Drug: D00066
PubChem Compound: 5994
RxNorm Ingredient: 8727
SNOMED-CT Concept: 16683002
Progesterone (substance)
UNII Identifier: 4G7DS2Q64Y
PROGESTERONE

Medicines

Progesterone is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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