Propafenone

Chemical formula: C₂₁H₂₇NO₃  Molecular mass: 341.444 g/mol  PubChem compound: 4932

Therapeutic indications

Propafenone is indicated for:

Ventricular arrhythmias, paroxysmal supraventricular tachyarrhythmias

Population group: only adults (18 years old or older)

Propafenone is indicated for the prophylaxis and treatment of ventricular arrhythmias.

Propafenone is also indicated for the prophylaxis and treatment of paroxysmal supraventricular tachyarrhythmias which include paroxysmal atrial flutter/fibrillation and paroxysmal re-entrant tachycardias involving the AV node or accessory bypass tracts, when standard therapy has failed or is contra-indicated.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Propafenone is contraindicated in the following cases:

Brugada Syndrome

Brugada syndrome

Myocardial infarction

at least one of
Myocardial infarction
Recent myocardial infarction

Uncontrolled congestive heart failure, cardiogenic shock

at least one of
Congestive heart failure
Cardiogenic shock

Severe symptomatic bradycardia

Severe sinus bradycardia

Severe obstructive pulmonary disease

Severe chronic obstructive pulmonary disease

Severe hypotension

Hypotension

Myasthenia gravis

Myasthenia gravis

Sinus node dysfunction

Coronary sinus rhythm disorder

Second degree AV block

Second degree atrioventricular block

Bundle branch block

Bundle branch block

Ritonavir

Ritonavir

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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