Chemical formula: C₇H₁₀N₂OS Molecular mass: 170.232 g/mol PubChem compound: 657298
Propylthiouracil is an antithyroid drug that depresses the formation of thyroid hormone. This is effected by interference both with the incorporation of iodine into tyrosyl residues and the coupling of such residues to form iodothyronines. Propylthiouracil achieves these actions by the inhibition of the enzyme peroxidase.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| H03BA02 | Propylthiouracil | H Systemic hormonal preparations, excl. Sex hormones and insulins → H03 Thyroid therapy → H03B Antithyroid preparations → H03BA Thiouracils |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PROPYLTHIOURACIL Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Propylthiouracil is an active ingredient of these brands:
Austria (AT)Brazil (BR)Cyprus (CY)France (FR)Hong Kong (HK)Malta (MT)Singapore (SG)Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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