Quinapril

Chemical formula: C₂₅H₃₀N₂O₅  Molecular mass: 438.516 g/mol  PubChem compound: 54892

Therapeutic indications

Quinapril is indicated for:

Essential hypertension

Population group: only adults (18 - 65 years old)

For the treatment of all grades of essential hypertension. Quinapril is effective as monotherapy or concomitantly with diuretics in patients with hypertension.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Congestive heart failure

Population group: only adults (18 - 65 years old)

For the treatment of congestive heart failure when given concomitantly with a diuretic and/or cardiac glycoside. Treatment of congestive heart failure with quinapril should always be initiated under close medical supervision.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Essential hypertension

Population group: only elderly (65 years old or older)

For the treatment of all grades of essential hypertension. Quinapril is effective as monotherapy or concomitantly with diuretics in patients with hypertension.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Congestive heart failure

Population group: only elderly (65 years old or older)

For the treatment of congestive heart failure when given concomitantly with a diuretic and/or cardiac glycoside. Treatment of congestive heart failure with quinapril should always be initiated under close medical supervision.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Quinapril is contraindicated in the following cases:

Pregnancy

Pregnancy

Idiopathic angioedema

Idiopathic angio-oedema

Left ventricular outflow obstruction

LVOTO - Left ventricular outflow tract obstruction

Aliskiren in diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m²)

Aliskiren and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Sacubitril, valsartan

at least one of
Sacubitril
Valsartan

Hereditary angioedema

Hereditary angioneurotic edema

Angiotensin converting enzyme inhibitor-aggravated angioedema

ACE inhibitor-aggravated angio-oedema

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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