Rabeprazole Other names: Rabeprazole sodium

Chemical formula: C₁₈H₂₁N₃O₃S  Molecular mass: 359.443 g/mol  PubChem compound: 5029

Active ingredient description

Rabeprazole belongs to the class of anti-secretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonist properties, but suppress gastric acid secretion by the specific inhibition of the H+/K+ -ATPase enzyme (the acid or proton pump).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A02BC04 Rabeprazole A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BC Proton pump inhibitors
Discover more medicines within A02BC04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
RABEPRAZOLE ACCORD Gastro-resistant tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ACIPHEX Delayed-release tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
ACIPHEX SPRINKLE Delayed-release capsule FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 117976-89-3
DrugBank Drug: DB01129
KEGG Drug: D08463
PubChem Compound: 5029
RxNorm Ingredient: 114979
SNOMED-CT Concept: 422225001
Rabeprazole (substance)
UNII Identifier: 32828355LL
RABEPRAZOLE
UNII Identifier: 3L36P16U4R
RABEPRAZOLE SODIUM

Medicines

Rabeprazole is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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