Chemical formula: C₁₂H₁₃N Molecular mass: 171.238 g/mol PubChem compound: 3052776
Rasagiline was shown to be a potent, irreversible MAO-B selective inhibitor, which may cause an increase in extracellular levels of dopamine in the striatum. The elevated dopamine level and subsequent increased dopaminergic activity are likely to mediate rasagiline’s beneficial effects seen in models of dopaminergic motor dysfunction.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N04BD02 | Rasagiline | N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BD Monoamine oxidase B inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RASAGILINE MYLAN Tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Rasagiline is an active ingredient of these brands:
United States (US)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)Cyprus (CY)Ecuador (EC)Estonia (EE)France (FR)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)Japan (JP)
Lithuania (LT)Malta (MT)
Mexico (MX)
Netherlands (NL)
Poland (PL)Romania (RO)
Singapore (SG)
South Africa (ZA)Spain (ES)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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