Regorafenib

Chemical formula: C₂₁H₁₅ClF₄N₄O₃  Molecular mass: 482.815 g/mol  PubChem compound: 11167602

Therapeutic indications

Regorafenib is indicated for:

Colorectal cancer (CRC)

Population group: only adults (18 years old or older)

Regorafenib is indicated as monotherapy for the treatment of adult patients with metastatic colorectal cancer (CRC) who have been previously treated with, or are not considered candidates for, available therapies. These include fluoropyrimidine-based chemotherapy, an anti-VEGF therapy and an anti-EGFR therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Gastrointestinal stromal tumours (GIST)

Population group: only adults (18 years old or older)

Regorafenib is indicated as monotherapy for the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumours (GIST) who progressed on or are intolerant to prior treatment with imatinib and sunitinib.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hepatocellular carcinoma (HCC)

Population group: only adults (18 years old or older)

Regorafenib is indicated as monotherapy for the treatment of adult patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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