Rifaximin

Chemical formula: C₄₃H₅₁N₃O₁₁  Molecular mass: 785.879 g/mol  PubChem compound: 6436173

Active ingredient description

Rifaximin is an antibacterial agent of the rifamycin class that inhibits bacterial RNA synthesis. Rifaximin has a broad antimicrobial spectrum against most of the Gram-positive and -negative, aerobic and anaerobic bacteria responsible for intestinal infections.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
A07AA11 Rifaximin A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07A Intestinal antiinfectives → A07AA Antibiotics
Discover more medicines within A07AA11
D06AX11 Rifaximin D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AX Other antibiotics for topical use
Discover more medicines within D06AX11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 XIFAXAN Tablet MPI, US: SPL/PLR FDA, National Drug Code (US)
 XIFANANTA Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 TARGAXAN Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 80621-81-4
DrugBank Drug: DB01220
KEGG Drug: D02554
PubChem Compound: 6436173
RxNorm Ingredient: 35619
SNOMED-CT Concept: 412553001
Rifaximin (substance)
UNII Identifier: L36O5T016N
RIFAXIMIN

Medicines

Rifaximin is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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