Rilpivirine

Chemical formula: C₂₂H₁₈N₆  Molecular mass: 366.419 g/mol  PubChem compound: 6451164

Therapeutic indications

Rilpivirine is indicated for:

Human immunodeficiency virus type 1 infection

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Rilpivirine, in combination with other antiretroviral medicinal products, is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in antiretroviral treatment-naïve patients 12 years of age and older with a viral load ≤100,000 HIV-1 RNA copies/ml.

Genotypic resistance testing should guide the use of rilpivirine.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Rilpivirine is contraindicated in the following cases:

Carbamazepine, oxcarbazepine, phenobarbital, phenytoin

at least one of
Carbamazepine
Oxcarbazepine
Phenobarbital
Phenytoin

Rifampicin

Rifampicin

Rifapentine

Rifapentine

Proton pump inhibitors

Proton pump inhibitors

Dexamethasone, except as a single dose treatment

Dexamethasone

St John's wort

Hypericum perforatum (St John's Wort)

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

Summary of Product Characteristics (SPC) 2022: EDURANT Film-coated tablet
< Previous: Overview
Next: Precautions >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈