Rizatriptan

Chemical formula: C₁₅H₁₉N₅  Molecular mass: 269.345 g/mol  PubChem compound: 5078

Therapeutic indications

Rizatriptan is indicated for:

Headache phase of migraine attacks with or without aura

Population group: only adults (18 years old or older)

Acute treatment of the headache phase of migraine attacks with or without aura in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Rizatriptan is contraindicated in the following cases:

Monoamine oxidase (MAO) inhibitors

Monoamine oxidase inhibitors (MAOIs)

Severe hepatic insufficiency, severe renal insufficiency

at least one of
Hepatic failure stage IV

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Cerebrovascular accident (CVA), transient ischaemic attack (TIA)

at least one of
CVA - Cerebrovascular accident
Temporary cerebral vascular dysfunction
H/O: CVA
History of transient ischemic attack

Hypertension

at least one of
Moderate pulmonary hypertension
Severe pulmonary hypertension
Mild pulmonary hypertension

Coronary artery disease, ischaemic heart disease, Prinzmetal's angina

at least one of
Coronary arteriosclerosis
Ischemic heart disease
Prinzmetal angina

Peripheral vascular disease

Peripheral vascular disease

Ergotamine, ergot derivatives, other 5-HT 1B/1D receptor agonists

at least one of
Ergotamine
Dihydroergotamine
Methysergide
Almotriptan
Eletriptan
Frovatriptan
Naratriptan
Oxitriptan
Sumatriptan
Zolmitriptan
Ergot alkaloids

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