Rotigotine

Chemical formula: C₁₉H₂₅NOS  Molecular mass: 315.48 g/mol  PubChem compound: 59227

Active ingredient description

Rotigotine is a non-ergolinic dopamine agonist for the treatment of signs and symptoms of Parkinson’s disease and Restless Legs Syndrome.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
N04BC09 Rotigotine N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BC Dopamine agonists
Discover more medicines within N04BC09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 NEUPRO 2mg/24h Transdermal patch MPI, EU: SmPC European Medicines Agency (EU)
 NEUPRO 1mg/24h, 3mg/24h Transdermal patch MPI, EU: SmPC European Medicines Agency (EU)
 NEUPRO 4mg/24h, 6mg/24h, 8mg/24h Transdermal patch MPI, EU: SmPC European Medicines Agency (EU)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 99755-59-6
DrugBank Drug: DB05271
KEGG Drug: D05768
PubChem Compound: 59227
RxNorm Ingredient: 616739
SNOMED-CT Concept: 421924006
Rotigotine (substance)
UNII Identifier: 87T4T8BO2E
ROTIGOTINE

Medicines

Rotigotine is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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