Chemical formula: C₁₉H₁₈FN₃O Molecular mass: 323.371 g/mol PubChem compound: 9931954
Rucaparib is indicated for:
Population group: only adults (18 years old or older)
Rucaparib is indicated as monotherapy for the maintenance treatment of adult patients with platinum-sensitive relapsed high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in response (complete or partial) to platinum-based chemotherapy.
Rucaparib is indicated as monotherapy treatment of adult patients with platinum sensitive, relapsed or progressive, BRCA mutated (germline and/or somatic), high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer, who have been treated with two or more prior lines of platinum based chemotherapy, and who are unable to tolerate further platinum based chemotherapy.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Rucaparib is contraindicated in the following cases:
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