Chemical formula: C₂₄H₂₉NO₅ Molecular mass: 411.498 g/mol PubChem compound: 9811834
Sacubitril is a prodrug and its active metabolite, LBQ657, inhibits neprilysin (neutral endopeptidase; NEP). The complementary cardiovascular benefits in heart failure patients are attributed to the enhancement of peptides that are degraded by neprilysin, such as natriuretic peptides (NP), by LBQ657.
Sacubitril is an active ingredient of these brands:
United States (US)
Australia (AU)
Brazil (BR)
Canada (CA)
Cyprus (CY)
Ecuador (EC)
Finland (FI)
France (FR)
Hong Kong (HK)
Israel (IL)
Italy (IT)
Japan (JP)
Netherlands (NL)
New Zealand (NZ)
Romania (RO)
Singapore (SG)
Tunisia (TN)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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