Chemical formula: C₂₆H₃₂N₄O₄S Molecular mass: 496.63 g/mol PubChem compound: 9913767
Selexipag is indicated for:
Population group: only adults (18 years old or older)
Uptravi is indicated for the long-term treatment of pulmonary arterial hypertension (PAH) in adult patients with WHO functional class (FC) II–III, either as combination therapy in patients insufficiently controlled with an endothelin receptor antagonist (ERA) and/or a phosphodiesterase type 5 (PDE-5) inhibitor, or as monotherapy in patients who are not candidates for these therapies.
Efficacy has been shown in a PAH population including idiopathic and heritable PAH, PAH associated with connective tissue disorders, and PAH associated with corrected simple congenital heart disease.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Selexipag is contraindicated in the following cases:
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