Chemical formula: C₆H₁₂ClNO Molecular mass: 149.619 g/mol PubChem compound: 3085017
Sevelamer is a non-absorbed phosphate binding crosslinked polymer, free of metal and calcium. Sevelamer contains multiple amines separated by one carbon from the polymer backbone which become protonated in the stomach. These protonated amines bind negatively charged ions such as dietary phosphate in the intestine.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| V03AE02 | Sevelamer | V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RENVELA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Sevelamer is an active ingredient of these brands:
Australia (AU)Ecuador (EC)Finland (FI)
Israel (IL)
Mexico (MX)New Zealand (NZ)Singapore (SG)
South Africa (ZA)
Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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