Chemical formula: C₄₉H₆₂N₁₀O₁₆S₃ Molecular mass: 1,143.27 g/mol PubChem compound: 9833444
Sincalide is a cholecystopancreatic-gastrointestinal hormone peptide for parenteral administration. The agent is a synthetically-prepared C-terminal octapeptide of cholecystokinin. When injected intravenously, sincalide stimulates gallbladder contraction and reduction in size. The evacuation of bile that results is similar to that which occurs physiologically in response to endogenous cholecystokinin. Sincalide also stimulates pancreatic secretion and intestinal motility causing pyloric contraction and slows gastric emptying.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| V04CC03 | Sincalide | V Various → V04 Diagnostic agents → V04C Other diagnostic agents → V04CC Tests for bile duct patency |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| KINEVAC Powder for solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Sincalide is an active ingredient of these brands:
United States (US)Canada (CA)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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