Sitagliptin

Chemical formula: C₁₆H₁₅F₆N₅O  Molecular mass: 407.314 g/mol  PubChem compound: 4369359

Active ingredient description

Sitagliptin is a member of a class of oral anti-hyperglycaemic agents called dipeptidyl peptidase 4 (DPP-4) inhibitors. The improvement in glycaemic control observed with this medicinal product may be mediated by enhancing the levels of active incretin hormones.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A10BH01 Sitagliptin A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors
Discover more medicines within A10BH01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
JANUVIA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 486460-32-6
CAS Substance: 654671-77-9
DrugBank Drug: DB01261
KEGG Drug: D08516
PubChem Compound: 4369359
RxNorm Ingredient: 593411
SNOMED-CT Concept: 423307000
Sitagliptin (substance)
UNII Identifier: QFP0P1DV7Z
SITAGLIPTIN

Medicines

Sitagliptin is an active ingredient of these brands:

United States (US)

  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE

Australia (AU)

  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE

Austria (AT)

Brazil (BR)

  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • NIMEGON as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) NIMEGON MET as SITAGLIPTIN PHOSPHATE

Canada (CA)

  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE

Croatia (HR)

Cyprus (CY)

  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • JIDINUM as SITAGLIPTIN HYDROCHLORIDE MONOHYDRATE
  • JIMANDIN as SITAGLIPTIN PHOSPHATE
  • TYBETA as Sitagliptin phosphate monohydrate

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE

Ecuador (EC)

  • ALTUXERIN as SITAGLIPTIN HYDROCHLORIDE
  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) GENNEO as SITAGLIPTIN PHOSPHATE
  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE

Estonia (EE)

Finland (FI)

  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • XELEVIA as Sitagliptin phosphate monohydrate

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE
  • (combination) VELMETIA

France (FR)

  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • XELEVIA as Sitagliptin phosphate monohydrate

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE
  • (combination) VELMETIA

Hong Kong (HK)

  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE

Ireland (IE)

Israel (IL)

  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • SITAR as SITAGLIPTIN HYDROCHLORIDE

  • (combination) JANUET as SITAGLIPTIN PHOSPHATE
  • (combination) SITAR PLUS as SITAGLIPTIN HYDROCHLORIDE
  • (combination) STEGLUJAN as SITAGLIPTIN PHOSPHATE

Italy (IT)

Japan (JP)

  • GLACTIV as SITAGLIPTIN PHOSPHATE
  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) SUJANU as SITAGLIPTIN PHOSPHATE

Lithuania (LT)

Malta (MT)

Mexico (MX)

  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE

Netherlands (NL)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

  • JANUVIA as SITAGLIPTIN PHOSPHATE

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

  • ARLIPTIN as SITAGLIPTIN HYDROCHLORIDE MONOHYDRATE
  • GLUVIA as SITAGLIPTIN HYDROCHLORIDE MONOHYDRATE
  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • PTIAGLIN as SITAGLIPTIN PHOSPHATE ANHYDROUS
  • SANOSITA as SITAGLIPTIN L-MALATE
  • XELEVIA as Sitagliptin phosphate monohydrate

  • (combination) ARLIPTIN MET as SITAGLIPTIN HYDROCHLORIDE MONOHYDRATE
  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE
  • (combination) SANOSITA PLUS as SITAGLIPTIN HYDROCHLORIDE
  • (combination) VELMETIA

United Kingdom (UK)

  • JANUVIA as SITAGLIPTIN PHOSPHATE
  • RISTABEN as SITAGLIPTIN PHOSPHATE
  • XELEVIA as Sitagliptin phosphate monohydrate

  • (combination) JANUMET as SITAGLIPTIN PHOSPHATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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