Chemical formula: NaNOâ‚‚ Molecular mass: 47.013 g/mol PubChem compound: 23668193
Sodium nitrite is indicated for sequential use with sodium thiosulfate for the treatment of acute cyanide poisoning that is judged to be life-threatening. Sodium nitrite is thought to exert its therapeutic effect by reacting with hemoglobin to form methemoglobin, an oxidized form of hemoglobin incapable of oxygen transport but with high affinity for cyanide.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| V03AB08 | Sodium nitrite | V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AB Antidotes |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SODIUM NITRITE Solutions for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Sodium nitrite is an active ingredient of these brands:
Ireland (IE)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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