Somatorelin

Chemical formula: C₂₁₅H₃₅₈N₇₂O₆₆S  Molecular mass: 5,038.666 g/mol 

Pharmacodynamic properties

Somatorelin is normally synthesised in the hypothalamus and stimulates the secretion of growth hormone from the pituitary gland. GHRH is the synthetic form of somatorelin and is identical in structure and function to somatorelin released by the human hypothalamus. Somatorelin physiologically increases plasma growth hormone levels.

Pharmacokinetic properties

After intravenous application of different doses of somatorelin in man, the concentrations of somatorelin in plasma increase within 5 minutes to the maximum value, followed by a rapid decrease. The basal values are reached again after 30-40 minutes.

Preclinical safety data

Not applicable.

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