Sotatercept

Therapeutic indications

Sotatercept is indicated for:

Pulmonary arterial hypertension

Population group: only adults (18 years old or older)

Sotatercept is indicated for the treatment of adults with pulmonary arterial hypertension (PAH, World Health Organization [WHO] Group 1) to increase exercise capacity, improve WHO functional class (FC), and reduce the risk of clinical worsening events.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

0.3 mg/kg once every 3 weeks and, after verifying acceptable Hgb and platelet count, 0.7 mg/kg once every 3 weeks

Contraindications

Sotatercept is contraindicated in the following cases:

Lactation

Platelet count <50,000/mm³

Platelet count below reference range

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