Tafenoquine

Chemical formula: C₂₄H₂₈F₃N₃O₃  Molecular mass: 463.501 g/mol 

Active ingredient description

Tafenoquine is an 8-aminoquinoline antimalarial drug. It is used for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged 16 years and older who are receiving chloroquine therapy for acute P. vivax infection.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
P01BA07 P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01B Antimalarials → P01BA Aminoquinolines
Discover more medicines within P01BA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
KRINTAFEL Film‑coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 106635-80-7
DrugBank Drug: DB06608
RxNorm Ingredient: 2054023
SNOMED-CT Concept: 773236009
Tafenoquine (substance)
UNII Identifier: 262P8GS9L9
TAFENOQUINE

Medicines

Tafenoquine is an active ingredient of these brands:

United States (US)

Brazil (BR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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