Tazarotene

Chemical formula: C₂₁H₂₁NO₂S  Molecular mass: 351.462 g/mol  PubChem compound: 5381

Active ingredient description

Tazarotene, a member of the acetylenic class of retinoids, is a prodrug which is converted to its active free form, tazarotenic acid, by de-esterification in the skin area. Tazarotenic acid is the only known metabolite of tazarotene to have retinoid activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D05AX05 Tazarotene D Dermatologicals → D05 Antipsoriatics → D05A Antipsoriatics for topical use → D05AX Other antipsoriatics for topical use
Discover more medicines within D05AX05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TAZORAC Gel FDA, National Drug Code (US) MPI, US: SPL/PLR
ZORAC Gel Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
TAZORAC Cream FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 118292-40-3
DrugBank Drug: DB00799
KEGG Drug: D01132
PubChem Compound: 5381
RxNorm Ingredient: 83947
SNOMED-CT Concept: 332218002
Tazarotene (substance)
SNOMED-CT Concept: 386935009
Tazarotene (substance)
UNII Identifier: 81BDR9Y8PS
TAZAROTENE

Medicines

Tazarotene is an active ingredient of these brands:

United States (US)

Canada (CA)

New Zealand (NZ)

Poland (PL)

Spain (ES)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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