Chemical formula: C₂₆H₅₆N₈O₄Tc₂ Molecular mass: 742.255 g/mol
When technetium Tc 99m pertechnetate is added to exametazime in the presence of stannous reductant, a lipophilic technetium Tc 99m complex is formed. This lipophilic complex is the active moiety. The lipophilic technetium Tc 99m exametazime complex is taken up and retained in leukocytes. It is used for leukocyte (white blood cell) labeled scintigraphy as an adjunct in the localization of intra-abdominal infection and inflammatory bowel disease.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| V09AA01 | Technetium (99mTc) exametazime | V Various → V09 Diagnostic radiopharmaceuticals → V09A Central nervous system → V09AA Technetium (99mTc) compounds |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DRAX EXAMETAZIME Kit, Powder for solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Technetium ⁹⁹ᵐTc exametazime is an active ingredient of these brands:
United States (US)
Austria (AT)
Cyprus (CY)
Estonia (EE)Hong Kong (HK)
Ireland (IE)
Lithuania (LT)
Malta (MT)
Singapore (SG)
Spain (ES)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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