Technetium ⁹⁹ᵐTc tetrofosmin

Chemical formula: C₁₈H₄₀O₄P₂Tc  Molecular mass: 898.86 g/mol  PubChem compound: 131704316

Active ingredient description

Technetium (99mTc) tetrofosmin is a lipophilic, cationic complex which diffuses passively through the cell membrane and is locally retained actively due to the presence of intact mitochondria reflecting the presence of viable cells. After intravenous injection, it is distributed within the myocardium according to myocardial perfusion and viability. It is used for Myocardial Perfusion Imaging and Ventricular Function Imaging.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V09GA02 Technetium (99mTc) tetrofosmin V Various → V09 Diagnostic radiopharmaceuticals → V09G Cardiovascular system → V09GA Technetium (99mTc) compounds
Discover more medicines within V09GA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MYOVIEW Kit, Powder for solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 127455-27-0
DrugBank Drug: DB09160
KEGG Drug: D06050
PubChem Compound: 131704316
SNOMED-CT Concept: 424118002
Technetium (99m-Tc) tetrofosmin (substance)
UNII Identifier: 42FOP1YX93
TECHNETIUM TC-99M TETROFOSMIN

Medicines

Technetium ⁹⁹ᵐTc tetrofosmin is an active ingredient of these brands:

United States (US)

Austria (AT)

Cyprus (CY)

Estonia (EE)

France (FR)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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