Telbivudine Other names: Epavudine L-deoxythymidine Beta-l-thymidine

Chemical formula: C₁₀H₁₄N₂O₅  Molecular mass: 242.229 g/mol  PubChem compound: 159269

Therapeutic indications

Telbivudine is indicated for:

Chronic hepatitis B

Population group: only adults (18 years old or older)

Telbivudine is indicated for the treatment of chronic hepatitis B in adult patients with compensated liver disease and evidence of viral replication, persistently elevated serum alanine aminotransferase (ALT) levels and histological evidence of active inflammation and/or fibrosis.

Initiation of telbivudine treatment should only be considered when the use of an alternative antiviral agent with a higher genetic barrier to resistance is not available or appropriate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Telbivudine is contraindicated in the following cases:

Interferon alfa

at least one of
Interferon alfa natural
Interferon alfa-2a
Interferon alfa-2b
Interferon alfa-n1
Peginterferon alfa-2a
Peginterferon alfa-2a, combinations
Peginterferon alfa-2b
Peginterferon-alfa-2b, combinations

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