Chemical formula: C₂₁H₂₅N Molecular mass: 291.43 g/mol PubChem compound: 1549008
Terbinafine is an allylamine which has a broad spectrum of antifungal activity. Terbinafine acts by inhibition of squalene epoxidase in the fungal cell membrane. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. The activity versus yeasts is fungicidal or fungistatic depending on the species.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D01AE15 | Terbinafine | D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AE Other antifungals for topical use |
| D01BA02 | Terbinafine | D Dermatologicals → D01 Antifungals for dermatological use → D01B Antifungals for systemic use → D01BA Antifungals for systemic use |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LAMISIL Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| TERBINAFINE MYLAN Cream | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| TERBINAFINE ACCORD Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Terbinafine is an active ingredient of these brands:
Albania (AL)Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)Cyprus (CY)
Ecuador (EC)
Estonia (EE)Finland (FI)
France (FR)
Germany (DE)Hong Kong (HK)
Ireland (IE)Japan (JP)
Lithuania (LT)Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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