Tinidazole

Chemical formula: C₈H₁₃N₃O₄S Molecular mass: 247.272 g/mol PubChem compound: 5479

Therapeutic indications

Tinidazole is indicated for:

Helicobacter pylori associated with duodenal ulcer

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Eradication of Helicobacter pylori associated with duodenal ulcers, in the presence of antibiotic and acid suppressant therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000 mg in 2 divided doses daily

Intraperitoneal infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Intraperitoneal infections: peritonitis, abscess.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000-2,000 mg in 2 divided doses daily

Gynaecological infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Gynaecological infections: endometritis, endomyometritis, tube-ovarian abscess.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000-2,000 mg in 2 divided doses daily

Bacterial septicaemia

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Bacterial septicemia and additionally Tinidazole susceptible species

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000-2,000 mg in 2 divided doses daily

Post-operative wound infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Postoperative wound infection and additionally Tinidazole susceptible species

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000-2,000 mg in 2 divided doses daily

Skin and soft tissue infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Soft tissue infection and additionally Tinidazole susceptible species

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000-2,000 mg in 2 divided doses daily

Upper and lower respiratory tract infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Upper and lower respiratory tract infections: pneumonia, empyema, lung abscess.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,000-2,000 mg in 2 divided doses daily

Non-specific vaginitis

Population group: women, only adolescents (12 years - 18 years old) , adults (18 years old or older)

Vaginitis and additionally Tinidazole susceptible species

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2,000 mg once

Acute ulcerative gingivitis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Acute ulcerative gingivitis and additionally Tinidazole susceptible species

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2,000 mg once

Urogenital trichomoniasis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Urogenital infection by Trichomonas vaginalis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2,000 mg once

Giardiasis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Giardiasis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2,000 mg once

Intestinal amoebiasis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Amoebic dysentery

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2,000 mg once daily

Amoebic involvement of the liver

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Amebic liver abscess

For this indication, competent medicine agencies globally authorize below treatments (click for details):

1,500-2,000 mg once daily

Prophylaxis of post-operative infections associated with colonic, gastro-intestinal and gynaecological surgery

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

The prevention of post-operative infections caused by anaerobic bacteria, especially those associated with colonic, gastro-intestinal and gynaecological surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2,000 mg once

Urogenital trichomoniasis

Population group: only children (1 year - 12 years old)

Urogenital infection by Trichomonas vaginalis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

75 mg/kg once

Giardiasis

Population group: only children (1 year - 12 years old)

Giardiasis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

75 mg/kg once

Intestinal amoebiasis

Population group: only children (1 year - 12 years old)

Amoebic dysentery

For this indication, competent medicine agencies globally authorize below treatments (click for details):

50-60 mg/kg once daily

Amoebic involvement of the liver

Population group: only children (1 year - 12 years old)

Amebic liver abscess

For this indication, competent medicine agencies globally authorize below treatments (click for details):

50-60 mg/kg once daily

Contraindications

Tinidazole is contraindicated in the following cases:

Blood dyscrasia

Blood disease

Pregnancy

Pregnancy

Lactation

Lactation

Organic neurological disorders

Neurological disorder

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