Chemical formula: C₂₂H₃₆N₂O₅S Molecular mass: 440.597 g/mol PubChem compound: 60947
Tirofiban is a non-peptidal antagonist of the GP IIb/IIIa receptor, an important platelet surface receptor involved in platelet aggregation. Tirofiban prevents fibrinogen from binding to the GP IIb/IIIa receptor, thus blocking platelet aggregation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B01AC17 | Tirofiban | B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AC Platelet aggregation inhibitors excl. heparin |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| TIROFIBAN Solution for infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Tirofiban is an active ingredient of these brands:
United States (US)
Australia (AU)
Austria (AT)
Brazil (BR)Canada (CA)
Cyprus (CY)
Ecuador (EC)Estonia (EE)
Finland (FI)
France (FR)Hong Kong (HK)
Israel (IL)
Lithuania (LT)
Malta (MT)
Netherlands (NL)
Singapore (SG)
Spain (ES)Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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