Tirzepatide

Therapeutic indications

Tirzepatide is indicated for:

Insufficiently controlled type 2 diabetes mellitus

Population group: only adults (18 years old or older)

Tirzepatide is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:

  • as monotherapy when metformin is considered inappropriate due to intolerance or contraindications.
  • in addition to other medicinal products for the treatment of diabetes.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Obesity or overweight in the presence of at least one weight-related comorbidity

Population group: only adults (18 years old or older)

Mounjaro is indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with an initial Body Mass Index (BMI) of

  • ≥30 kg/m² (obesity) or
  • ≥27 kg/m² to <30 kg/m² (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease, prediabetes, or type 2 diabetes mellitus).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Tirzepatide is contraindicated in the following cases:

Lactation

Lactation

Pancreatitis

Pancreatitis

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2024: MOUNJARO Solution for injection
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