Tocofersolan

Chemical formula: C₃₅H₅₈O₆  Molecular mass: 574.8 g/mol 

Active ingredient description

Vitamin E is the principal lipo-soluble antioxidant in the organism. It acts as a free radical chain breaking molecule, stopping the peroxidation of polyunsaturated fatty acids and it is involved in maintaining the stability and integrity of cell membranes. Tocofersolan is indicated in vitamin E deficiency due to digestive malabsorption in paediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A11HA08 Tocofersolan A Alimentary tract and metabolism → A11 Vitamins → A11H Other plain vitamin preparations → A11HA Other plain vitamin preparations
Discover more medicines within A11HA08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VEDROP Oral solution European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 9002-96-4
DrugBank Drug: DB11635
RxNorm Ingredient: 159151
UNII Identifier: O03S90U1F2
VITAMIN E POLYETHYLENE GLYCOL SUCCINATE

Medicines

Tocofersolan is an active ingredient of these brands:

Austria (AT)

  • VEDROP as .ALPHA.-TOCOPHEROL

Croatia (HR)

  • VEDROP as .ALPHA.-TOCOPHEROL

Estonia (EE)

  • VEDROP as .ALPHA.-TOCOPHEROL

Finland (FI)

  • VEDROP as .ALPHA.-TOCOPHEROL

France (FR)

  • VEDROP as .ALPHA.-TOCOPHEROL

Ireland (IE)

  • VEDROP as .ALPHA.-TOCOPHEROL

Italy (IT)

  • VEDROP as .ALPHA.-TOCOPHEROL

Lithuania (LT)

  • VEDROP as .ALPHA.-TOCOPHEROL

Netherlands (NL)

  • VEDROP as .ALPHA.-TOCOPHEROL

Poland (PL)

  • VEDROP as .ALPHA.-TOCOPHEROL

Romania (RO)

  • VEDROP as .ALPHA.-TOCOPHEROL

Spain (ES)

  • VEDROP as .ALPHA.-TOCOPHEROL

United Kingdom (UK)

  • VEDROP as .ALPHA.-TOCOPHEROL

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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