Topiramate

Chemical formula: C₁₂H₂₁NO₈S  Molecular mass: 339.362 g/mol  PubChem compound: 5284627

Therapeutic indications

Topiramate is indicated for:

Partial seizures, primary generalised tonic-clonic seizures, Lennox-Gastaut syndrome

Population group: only adults (18 years old or older)

Monotherapy in adults, adolescents and children over 6 years of age with partial seizures with or without secondary generalised seizures, and primary generalised tonic-clonic seizures.

Adjunctive therapy in children aged 2 years and above, adolescents and adults with partial onset seizures with or without secondary generalization or primary generalized tonic-clonic seizures and for the treatment of seizures associated with Lennox-Gastaut syndrome.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of migraine headache

Population group: only adults (18 years old or older)

Topiramate is indicated in adults for the prophylaxis of migraine headache after careful evaluation of possible alternative treatment options. Topiramate is not intended for acute treatment.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Partial seizures, primary generalised tonic-clonic seizures, Lennox-Gastaut syndrome

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Adjunctive therapy in children aged 2 years and above, adolescents and adults with partial onset seizures with or without secondary generalization or primary generalized tonic-clonic seizures and for the treatment of seizures associated with Lennox-Gastaut syndrome.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Topiramate is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.