Toremifene Other names: Toremifene citrate

Chemical formula: C₂₆H₂₈ClNO  Molecular mass: 405.96 g/mol  PubChem compound: 3005573

Active ingredient description

Toremifene is a nonsteroidal triphenylethylene derivative that binds to estrogen receptors and may produce estrogenic, anti-estrogenic or both effects, depending upon the duration of treatment, animal species, gender, target organ and variable selected. Toremifene is indicated in first line hormone treatment of hormone-dependent metastatic breast cancer in postmenopausal patients.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
L02BA02 Toremifene L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02B Hormone antagonists and related agents → L02BA Anti-estrogens
Discover more medicines within L02BA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 FARESTON Tablet MPI, EU: SmPC European Medicines Agency (EU)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 89778-26-7
DrugBank Drug: DB00539
PubChem Compound: 3005573
RxNorm Ingredient: 38409
SNOMED-CT Concept: 387588002
Toremifene (substance)
UNII Identifier: 7NFE54O27T
TOREMIFENE

Medicines

Toremifene is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Poland (PL)

Romania (RO)

South Africa (ZA)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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