Trabectedin

Chemical formula: C₃₉H₄₃N₃O₁₁S  Molecular mass: 761.837 g/mol  PubChem compound: 108150

Therapeutic indications

Trabectedin is indicated for:

Soft tissue sarcoma

Population group: only adults (18 years old or older)

Trabectedin is indicated for the treatment of adult patients with advanced soft tissue sarcoma, after failure of anthracyclines and ifosfamide, or who are unsuited to receive these agents. Efficacy data are based mainly on liposarcoma and leiomyosarcoma patients.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ovarian cancer

Population group: women, only adults (18 years old or older)

Trabectedin in combination with pegylated liposomal doxorubicin (PLD) is indicated for the treatment of patients with relapsed platinum-sensitive ovarian cancer.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Trabectedin is contraindicated in the following cases:

Yellow fever vaccine

Yellow fever vaccines

Lactation

Lactation

Infection

Infectious disease

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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