Trifluoperazine Other names: Trifluoperazine hydrochloride

Chemical formula: C₂₁H₂₄F₃N₃S Molecular mass: 407.496 g/mol PubChem compound: 5566

Therapeutic indications

Trifluoperazine is indicated for:

Psychoses, mental subnormality, nausea and vomiting

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Low dosage: Trifluoperazine is indicated as an adjunct in the short-term management of anxiety states, depressive symptoms secondary to anxiety and agitation. Orally it is also indicated in the symptomatic treatment of nausea and vomiting.

High dosage: Trifluoperazine is intended for the treatment of symptoms and prevention of relapse in schizophrenia and in other psychoses, especially of the paranoid type, but not in depressive psychoses. It may also be used as an adjunct in short-term management of severe psychomotor agitation and of dangerously impulsive behaviour in, for example, mental subnormality.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2-4 mg a day in divided doses or 10 mg a day, increased to 15 mg after a week and thereafter further increases of 5 mg at three-day intervals

1-5 mg daily given in divided doses

1-2 mg a day in divided doses or 5 mg a day, increased to 10 mg after a week and thereafter further increases of 5 mg at three-day intervals

Contraindications

Trifluoperazine is contraindicated in the following cases:

Liver damage

at least one of

Hepatic insufficiency
Hepatopathy

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