Trimebutine

Chemical formula: C₂₂H₂₉NO₅  Molecular mass: 387.476 g/mol  PubChem compound: 5573

Active ingredient description

Trimebutine maleate is a noncompetitive spasmolytic agent. It possesses moderate opiate receptor affinity and has a marked antiserotonin activity especially on ‘M’ receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig taenia coli and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A03AA05 Trimebutine A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03A DRUGS FOR FUNCTIONAL BOWEL DISORDERS → A03AA Synthetic anticholinergics, esters with tertiary amino group
Discover more medicines within A03AA05

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 39133-31-8
DrugBank Drug: DB09089
PubChem Compound: 5573
RxNorm Ingredient: 10819
SNOMED-CT Concept: 698184001
Trimebutine (substance)
UNII Identifier: QZ1OJ92E5R
TRIMEBUTINE

Medicines

Trimebutine is an active ingredient of these brands:

Brazil (BR)

Ecuador (EC)

France (FR)

Hong Kong (HK)

  • MABIN as TRIMEBUTINE MALEATE
  • POBUTIN as TRIMEBUTINE MALEATE
  • TRITIN as TRIMEBUTINE MALEATE

Japan (JP)

Mexico (MX)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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