Trimetazidine

Chemical formula: C₁₄H₂₂N₂O₃  Molecular mass: 266.341 g/mol  PubChem compound: 21109

Therapeutic indications

Trimetazidine is indicated for:

Stable angina pectoris

Population group: only adults (18 years old or older)

Trimetazidine is indicated in adults as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line antianginal therapies.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Trimetazidine is contraindicated in the following cases:

Parkinson disease, tremor, restless leg syndrome

at least one of
Parkinson's disease
Tremor
Restless legs

Severe renal impairment (creatinine clearance <30ml/min)

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) : TRIMETAZIDINE Prolonged-release tablets
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