Trimethadione

Chemical formula: C₆H₉NO₃  Molecular mass: 143.058 g/mol  PubChem compound: 5576

Active ingredient description

Trimethadione is an antiepileptic agent. Trimethadione has been shown to prevent pentylenetetrazol-induced and thujone-induced seizures in experimental animals; the drug has a less marked effect on seizures induced by picrotoxin, procaine, cocaine, or strychnine. Unlike the hydantoins and antiepileptic barbiturates, trimethadione does not modify the maximal seizure pattern in patients undergoing electroconvulsive therapy.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N03AC02 Trimethadione N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AC Oxazolidine derivatives
Discover more medicines within N03AC02

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 127-48-0
DrugBank Drug: DB00347
KEGG Drug: D00392
PubChem Compound: 5576
RxNorm Ingredient: 10827
SNOMED-CT Concept: 70732003
Trimethadione (substance)
UNII Identifier: R7GV3H6FQ4
TRIMETHADIONE

Medicines

Trimethadione is an active ingredient of these brands:

Japan (JP)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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