Ursodeoxycholic acid Other names: Ursodiol UDCA

Chemical formula: C₂₄H₄₀O₄  Molecular mass: 392.572 g/mol  PubChem compound: 31401

Therapeutic indications

Ursodeoxycholic acid is indicated for:

X-ray radiolucent (X-ray negative) gallstones

Population group: only adults (18 years old or older)

The dissolution of cholesterol stones in patients:

  • with one or more X-ray radiolucent (X-ray negative) gallstones, preferably with a diameter of not more than 2 cm, in a well-functioning gall bladder;
  • refusing a surgical procedure or in which surgical intervention is not indicated;
  • with whom an oversaturation of cholesterol has been shown by chemical analysis of the bile produced by duodenum drainage.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Primary biliary cholangitis

Population group: only adults (18 years old or older)

Primary biliary cirrhosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hepatobiliary disorder associated with cystic fibrosis

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Hepatobiliary disorder associated with cystic fibrosis in children aged 6 years to 18 years.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Ursodeoxycholic acid is contraindicated in the following cases:

Gastric ulcer, duodenal ulcer

at least one of
Gastric ulcer
Duodenal ulcer disease

Biliary colic

Biliary colic

Occlusion of the biliary tract

Obstruction of biliary tree

Inflammation of the gall bladder or bile ducts

Cholangitis

X-ray radiolucent calcified gallstones

Cholecystolithiasis

Impaired contractility of the gallbladder

at least one of
Dyskinesia of gallbladder
Atony of gallbladder

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

Summary of Product Characteristics (SPC) 2019: URSODEOXYCHOLIC ACID Tablet
Structured Product Labeling (SPL/PLR) 2018: URSO 250 / FORTE Film-coated tablet
< Previous: Overview
Next: Precautions >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈