Vadadustat

Chemical formula: C₁₄H₁₁ClN₂O₄  Molecular mass: 306.041 g/mol  PubChem compound: 23634441

Active ingredient description

Vadadustat is a hypoxia-inducible factor prolyl-hydroxylase inhibitor which leads to increased cellular levels of hypoxia-inducible factor thereby stimulating endogenous erythropoietin (EPO) production, increasing iron mobilization and red blood cell production, resulting in gradual rate of rise in Hb.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B03XA08 B Blood and blood forming organs → B03 Antianemic preparations → B03X Other antianemic preparations → B03XA Other antianemic preparations
Discover more medicines within B03XA08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VAFSEO Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1000025-07-9
DrugBank Drug: DB12255
KEGG Drug: D11078
PubChem Compound: 23634441
UNII Identifier: I60W9520VV
VADADUSTAT

Medicines

Vadadustat is an active ingredient of these brands:

Austria (AT)

Croatia (HR)

Estonia (EE)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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