Combination of three antihypertensive compounds with complementary mechanisms to control blood pressure in patients with essential hypertension: amlodipine that belongs to the calcium antagonist class and valsartan that belongs to the angiotensin II antagonist class of medicines and hydrochlorothiazide that belongs to the thiazide diuretics class of medicines. The combination of these substances has an additive antihypertensive effect.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09DX01 | Valsartan, amlodipine and hydrochlorothiazide | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09D Angiotensin II antagonists, combinations → C09DX Angiotensin II antagonists, other combinations |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| COPALIA HCT Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
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