Valsartan

Chemical formula: C₂₄H₂₉N₅O₃  Molecular mass: 435.519 g/mol  PubChem compound: 60846

Therapeutic indications

Valsartan is indicated for:

Essential hypertension

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Essential hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Left ventricular systolic dysfunction after a recent (12 hours - 10 days) myocardial infarction

Population group: only adults (18 years old or older)

Treatment of clinically stable adult patients with symptomatic heart failure or asymptomatic left ventricular systolic dysfunction after a recent (12 hours – 10 days) myocardial infarction.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Heart failure

Population group: only adults (18 years old or older)

Treatment of adult patients with symptomatic heart failure when ACE-inhibitors are not tolerated or in beta-blocker intolerant patients as add-on therapy to ACE-inhibitors when mineralocorticoid receptor antagonists cannot be used.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Valsartan is contraindicated in the following cases:

Severe hepatic impairment

Hepatic failure stage IV

Primary hyperaldosteronism

Primary hyperaldosteronism

Pregnancy

Pregnancy

Biliary cirrhosis

Biliary cirrhosis

Cholestasis

Cholestasis

Aliskiren in diabetes mellitus or renal impairment

Aliskiren and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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