Vedolizumab

Therapeutic indications

Vedolizumab is indicated for:

Ulcerative colitis

Population group: only adults (18 years old or older)

Vedolizumab is indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a tumour necrosis factor-alpha (TNFα) antagonist.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Crohn's disease

Population group: only adults (18 years old or older)

Vedolizumab is indicated for the treatment of adult patients with moderately to severely active Crohn’s disease who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a tumour necrosis factor-alpha (TNFα) antagonist.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Pouchitis

Population group: only adults (18 years old or older)

Vedolizumab is indicated for the treatment of adult patients with moderately to severely active chronic pouchitis, who have undergone proctocolectomy and ileal pouch anal anastomosis for ulcerative colitis, and have had an inadequate response with or lost response to antibiotic therapy

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Vedolizumab is contraindicated in the following cases:

Active severe infections

at least one of
Infectious disease
Tuberculosis
Systemic infection
Cytomegalovirus infection
Listeriosis
Progressive multifocal leukoencephalopathy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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