Pyridoxine Other names: Vitamin B6

Molecular mass: 169.178 g/mol  PubChem compound: 1054

Interactions

Pyridoxine interacts in the following cases:

Isoniazid, penicillamine, oral contraceptives

Many drugs may alter the metabolism or bioavailability of pyridoxine, including isoniazid, penicillamine and oral contraceptives, which may increase the requirements for pyridoxine.

Levodopa

Pyridoxine hydrochloride may reduce the effect of levodopa, a drug used in the treatment of Parkinsons disease unless a dopa decarboxylase inhibitor is also given.

Pregnancy

Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses on pregnancy or the health of the foetus or newborn child.

Animal studies are insufficient with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development.

Caution should be exercised when prescribing to pregnant women.

Nursing mothers

Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses during lactation.

Effects on ability to drive and use machines

None known.

Adverse reactions


Long term administration of large doses of pyridoxine is associated with the development of severe peripheral neuritis.

Cross-check medications

Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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