Volanesorsen

Chemical formula: C₂₃₀H₃₂₀N₆₃O₁₂₅P₁₉S₁₉  Molecular mass: 7,162.04 g/mol 

Active ingredient description

Volanesorsen is an antisense oligonucleotide designed to inhibit the formation of apoC-III, a protein that is recognised to regulate both triglyceride metabolism and hepatic clearance of chylomicrons and other triglyceride-rich lipoproteins.

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
WAYLIVRA Solution for injection European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 915430-78-3
DrugBank Drug: DB15067
KEGG Drug: D11648
UNII Identifier: 2O4BE0K238
VOLANESORSEN

Medicines

Volanesorsen is an active ingredient of these brands:

Austria (AT)

Croatia (HR)

Estonia (EE)

France (FR)

Ireland (IE)

Italy (IT)

Lithuania (LT)

Poland (PL)

Romania (RO)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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