Warfarin

Chemical formula: C₁₉H₁₆O₄  Molecular mass: 308.328 g/mol  PubChem compound: 54678486

Therapeutic indications

Warfarin is indicated for:

Prophylaxis of systemic embolism in rheumatic heart disease and atrial fibrillation

Population group: only adults (18 years old or older)

Preventive procedure and additionally Thromboembolic disorder and additionally at least one of
Rheumatic heart disease
Atrial fibrillation

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis and treatment of venous thrombosis and pulmonary embolism

Population group: only adults (18 years old or older)

at least one of
Venous thrombosis
Pulmonary embolism
Preventive procedure and additionally at least one of
Venous thrombosis
Pulmonary embolism

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Transient cerebal ischaemic attack

Population group: only adults (18 years old or older)

Temporary cerebral vascular dysfunction

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of thromboembolism after insertion of prosthetic heart valve

Population group: only adults (18 years old or older)

Preventive procedure and additionally Prosthetic cardiac valve thrombosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Warfarin is contraindicated in the following cases:

Haemorrhagic stroke

at least one of
Intracerebral haemorrhage
Subarachnoid haemorrhage from middle cerebral artery

Clinically significant bleeding

Bleeding

Within 72 hours of major surgery with risk of severe bleeding

Surgical and dental procedures

Within 48 hours postpartum

Delivery procedure

Pregnancy

Pregnancy

Fibrinolytic drugs

Enzymes

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Related medicines

Summary of Product Characteristics (SPC) 2017: WARFARIN Tablet
Structured Product Labeling (SPL/PLR) 2020: COUMADIN Tablet
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