Zanamivir
Chemical formula: C₁₂H₂₀N₄O₇ Molecular mass: 332.31 g/mol PubChem compound: 60855
Active ingredient description
Zanamivir is an inhibitor of influenza virus neuraminidase, an enzyme that releases viral particles from the plasma membrane of infected cells and promotes virus spread in the respiratory tract. The activity of zanamivir is extracellular. It reduces the propagation of both influenza A and B viruses by inhibiting the release of infectious influenza virions from the epithelial cells of the respiratory tract.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J05AH01 | Zanamivir | J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AH Neuraminidase inhibitors |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RELENZA Inhalation powder, pre-dispensed | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DECTOVA Solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
Medicines
Zanamivir is an active ingredient of these brands:
United States (US)Brazil (BR)Canada (CA)Croatia (HR)Ecuador (EC)France (FR)Hong Kong (HK)Japan (JP)Malta (MT)Mexico (MX)New Zealand (NZ)Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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